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HLSC 374: Mathematical Modeling in Biology

Fall, 2015
Biochemical oscillators
Lab files (.zip)

Papers discussed:

Tyson, J.J., Chen, K.C. & Novak, B., 2003. Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Current Opinion in Cell Biology, 15(2), pp.221–231.

Ma, L. et al., 2004. Two Complementary, Local Excitation, Global Inhibition Mechanisms Acting in Parallel Can Explain the Chemoattractant-Induced Regulation of PI(3,4,5)P. Biophysical Journal, 87(6), pp.3764–3774.

Best, J.A., Nijhout, H.F. & Reed, M.C., 2009. Homeostatic mechanisms in dopamine synthesis and release: a mathematical model. Theoretical Biology and Medical Modelling, 6(1), p.21.

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